Start With The Pattern
Antibody identification compares patient plasma reactivity against reagent donor cells with known antigen profiles. Nonreactive cells are especially useful because they help exclude antibody specificities.
Blood bank practice
Antibody identification for classic panel workups.
Learn the basic rule-out workflow, then practice with synthetic 11-cell donor panels and an autocontrol. This portfolio project is educational and is not medical decision support.
How The Workflow Fits Together
Use Nonreactive Cells To Rule Out
If a nonreactive donor cell carries an antigen, the corresponding antibody is less likely. The app tracks those exclusions so the remaining candidates become easier to see.
Respect Dosage
Some antibodies react more strongly with double-dose antigen expression. For Rh, MNS, Duffy, and Kidd examples, a homozygous rule-out is stronger than a heterozygous rule-out.
What To Look For
A negative autocontrol supports an alloantibody pattern. Positive panel reactions point toward cells that may carry the target antigen, while nonreactive antigen-positive cells support rule-out. The final answer should fit the reaction pattern and leave compatible antigen-negative donor options.